Тромбоцитарно-судинний гемостаз у хворих на інфаркт міокарда залежно від алельних варіантів генів АСЕ (I/D) та eNOS (894G>T). Вплив лікування

Автор(и)

  • J. V. Ursuliak
  • L. P. Sydorchuk

DOI:

https://doi.org/10.24061/2413-0737.XVIII.1.69.2014.32

Ключові слова:

інфаркт міокарда, гени АСЕ (І/ D), eNOS (T894G), гемостаз, лікування

Анотація

Проаналізовано зміни тромбоцитарно-судинного гемостазу під впливом базового лікування 102 хворих на гострий інфаркт міокарда (ГІМ) залежно від алельних варіантів генів ангіотензин-конвертуючого ферменту (АСЕ, I/D) та ендотеліальної NO-синтази (eNOS, 894G>T). Встановлена залежність ефективності терапії за впливом на ключові ланки гемостазу від генотипів та гаплотипів аналізованих генів.

Посилання

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2014-02-02

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